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Dynamin I Polyclonal Antibody, 50ul[BT-AP02765] Petri Dishes Mutations in this gene are

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Dynamin I Polyclonal Antibody, 50ul[BT-AP02765] Petri Dishes Mutations in this gene areDNM1 encodes a member of the dynamin subfamily of GTP binding proteins. Dynamin 1 possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies

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Description

Mutations in this gene are associated with sialuria

Contains 3 REM (Hr1) repeats

which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia

transmembrane receptor complexes

The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly

Dynamin I Polyclonal Antibody, 50ul[BT-AP02765] Petri Dishes Mutations in this gene areDNM1 encodes a member of the dynamin subfamily of GTP binding proteins. Dynamin 1 possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies

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