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Topical vitamin C: A useful agent for treating photoaging and other dermatologic conditions

In vitro studies have shown that curculigoside inhibits tartrate-resistant acid phosphatase activity in osteoblasts induced by RANKL or H 2 O 2 and reduces the expression of cathepsin K (Ctsk) and MMP-9

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In the presence of ongoing accumulation of A, a subset of microglia becomes abnormally activated, causing a neurotoxic effect that accelerates the progression of neurodegenerative diseases (100, 101)