HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 Liver fibrosis and hepatocyte apoptosis

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831

3-30 μM) significantly reduces both inward and outward components of IClCa

PubMed PMID: 24500879

MMTV/c-Neu female mice) treatment inhibits Smad/TGFβ signaling

Martindale C

HSD1590 - CAS# 2379279-96-4 Catalog No.:M6846-2 Liver fibrosis and hepatocyte apoptosisHSD1590, CAS No. 2379279 96 4, is potent ROCK inhibitor, with IC50s of 1. 22 and 0. 51 nM for ROCK1 and ROCK2, respectively. HSD1590 exhibits single digit nanomolar binding to ROCK (Kds<2 nM). HSD1590 displays low cytotoxicity. Product information CAS Number: 2379279 96 4 Molecular Weight: 359. 19 Formula: C20H18BN3O3 Chemical Name: HSD1590 Smiles: COC1C(=CC=CC=1C1=NC2=CC=C3NN=CC3=C2C2CCCC=21)B(O)O InChiKey: WTZMCUOBQPTERK UHFFFAOYSA N InChi: InChI=1S