CNX-1351 - CAS# 1276105-89-5 mic Acid 22-11-/t20-

22-11-/t20-

InChi: InChI=1S/C21H20N2O2/c1-15(19-4-3-5-20(14-19)25-2)23-21(24)18-8-6-16(7-9-18)17-10-12-22-13-11-17/h3-15H

14b-icosahydropicen-3-yl]oxy}-5-{[(2R

1357302-64-7

ZM-447439 selectively inhibits recombinant human Aurora A and B with IC50 values of 110 and 130 nM

CNX-1351 - CAS# 1276105-89-5 mic Acid 22-11-/t20-CNX 1351 is a selective covalent Inhibitor of PI3K. In an end point assay, CNX 1351 potently inhibited PI3K and was 20400 times less potent against , , and . CNX 1351 inhibit PI3K signaling in cells and shows prolonged inhibition consistent with a covalent mechanism of Action. CNX 1351 inhibits growth of cells dependent on PI3K. CNX 1351 also inhibits PI3K signaling in vivo and bonds to p110. Product information CAS Number: 1276105 89 5 Molecular