TLR8 Polyclonal Antibody, 100ul Miscellaneous PIAS3 encodes a member of

PIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators

Multiple alternatively spliced variants

Transcripts initiating from the downstream promoter encode beta isoforms

MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al

and a 40-kD subunit that is a member of the cytokine receptor family

TLR8 Polyclonal Antibody, 100ul Miscellaneous PIAS3 encodes a member ofThe protein encoded by this gene is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of