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Roland FB, Irwin WS

This process involves a decrease in nave T cells and an accumulation of memory T cells, impairing the immune systems ability to respond to novel or fast-mutating pathogens, such as influenza virus while preserving responsiveness to previously encountered ones [283]

2 Oxidative stress and periodontitis 2.1 Basic concepts of oxidative stress Oxidative stress refers to an imbalance between the production of reactive oxygen types (involving superoxide anions, hydrogen peroxide, etc.) and other oxidants in the cellular and extracellular environment, capable of damaging cell structures and functions (Albano et al., 2022)