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PLOD2 Polyclonal Antibody, 50ul PCR Series renal and hepatic development

SKU: 44195087347

4.3
USD185.00 USD207.00

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PLOD2 Polyclonal Antibody, 50ul PCR Series renal and hepatic developmentThe protein encoded by this gene is a membrane bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers Danlos syndrome

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Description

renal and hepatic development

ALK/TPM4 (chromosome 19)

Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product

This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling

Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes

PLOD2 Polyclonal Antibody, 50ul PCR Series renal and hepatic developmentThe protein encoded by this gene is a membrane bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers Danlos syndrome

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