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In clinical trials of Wegovy (FDA-approved semaglutide), participants achieved an average weight loss of approximately 15% over 68 weeks, with some participants achieving up to 20% with continued treatment and adherence, when combined with diet and exercise

Cognitive Enhancement Studies Research suggests potential cognitive benefits through NAD+ preservation in brain tissue, as NAD+ depletion impairs synaptic transmission and neuromuscular junction communication

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High doses of B12, often used to treat deficiencies, may cause side effects such as headaches, nausea, diarrhea, fatigue or weakness, and tingling in the hands and feet