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Both medications cause gastrointestinal side effects

With Savings Programmes Commercial insurance (both drugs): savings cards can reduce cost to as little as $25 per month Zepbound vials via LillyDirect: single-dose vials (self-drawn with a syringe) are significantly cheaper than pens Wegovy via NovoCare cash pricing: roughly $199$349 per month for uninsured/underinsured patients Insured but no weight-loss coverage: Zepbound may still cost ~$550/month through Lillys programme Important 2026 Cost News Oral Wegovy launched January 2026 a daily tablet at $149$299/month cash, a meaningful option for those who dislike injections Novo Nordisk announced a Wegovy list-price cut to ~$675/month from January 2027 (roughly 50% reduction) Foundayo (orforglipron) launched April 2026 the first oral GLP-1 with no food or water restrictions, ~$25/month with insurance

The decrease in calorie intake, as a result, contributes to substantial weight loss over time

Your provider may also check for other possible triggers, such as detergents, foods, or other drugs youre taking

Exercise preserves muscle and regulates appetite hormones