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Specifically, 40% in the 0.1-mg group, 36% in the 0.2-mg group, and 59% in the 0.4-mg group achieved this endpoint, compared to just 17% receiving placebo

Some studies have suggested that the proliferation and apoptosis of granulosa cells (GCs) are the root causes of follicular development and atresia, with forkhead box protein O1 (FoxO1) playing an important role in promoting PCOS follicular atresia and GCs apoptosis (162, 163)

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