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10.1038/s42003-020-0957-6 171 WenC.LiF.ZhangL.DuanY.GuoQ.WangW.et al

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Pro-inflammatory cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-), are central to the inflammatory cascade, directly influencing insulin resistance, endothelial cell activation, and plaque instability (7, 8)