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Glutathione protects astrocytes from peroxynitrite-mediated mitochondrial damage: implications for neuronal/astrocytic trafficking and neurodegeneration

Pioglitazone reversed elements of this signature, increasing PPARGC1A expression ( p = 0.099) and modulating downstream pathways in muscle, including enhanced oxidative phosphorylation

Patients consuming significantly fewer calories may not meet requirements for essential micronutrients, including B vitamins, iron, and vitamin D, all of which play crucial roles in energy metabolism