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Hypoglycemia (especially when used with insulin)

In STEP-1 (semaglutide), lean mass decreased by ~9.7% while fat mass fell by ~19.3%, with the proportion of lean mass increasing by ~3 percentage points (35)

Keep portions smaller and nutrient density high

3 Among firms with 5,000 or more workers, coverage had increased to 43% up from 28% the year prior but many of those employers reported that utilization was higher than expected and that covering the medications had a significant impact on 3 Several firms that initially offered coverage had since restricted it to employees with specific medical indications, such as type 2 diabetes, with some noting the challenge of removing a benefit that employees had come to rely on

These are your two best tools for preserving lean mass during the transition